Mild Copper-TBAF-Catalyzed N-Arylation of Sulfoximines with Aryl Siloxanes
Jaeeun Kim, Jinpyo Ok, Sanghyuck Kim, Wonseok Choi and Phil Ho Lee*
*Department of Chemistry, Kangwon National University, Chuncheon 200-701, Republic of Korea, Email: phleekangwon.ac.kr
J. Kim, J. Ok, S. Kim, W. Choi, P. H. Lee, Org. Lett., 2014, 16, 4602-4603.
DOI: 10.1021/ol502174n (free Supporting Information)
An efficient copper-TBAF-catalyzed arylation of sulfoximines with arylsiloxanes in dichloromethane at room temperature affords the desired N-aryl sulfoximines in good to excellent yields under an oxygen atmosphere. This mild C-N bond formation complements the existing approaches due to the advantageous properties of arylsiloxanes such as availability, low toxicity, ease of handling, high stability, and environmental benignity.
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