Regio- and Stereoselective Synthesis of 2,3,5-Trienoates by Palladium-Catalyzed Alkoxycarbonylation of Conjugated Enyne Carbonates
Ezgi Şule Karagöz, Melih Kuş, Gürkan Eray Akpınar and Levent Artok*
*Department of Chemistry, Faculty of Science, Izmir Institute
of Technology, Urla 35430, Izmir Turkey, Email: leventartok
iyte.edu.tr
E. Ş. Karagöz, M. Kuş, G. E. Akpınar, L. Artok, J. Org. Chem., 2014, 79, 9222-9230.
DOI: 10.1021/jo5014993
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Abstract
Palladium-catalyzed alkoxycarbonylation of 2,4-enyne carbonates proceeds in an alcohol and under balloon pressure of CO through 1,5-substitution. The olefin geometry controls the overall stereochemistry of this alkoxycarbonylation method.
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Palladium-Catalyzed Alkoxycarbonylation of (Z)-2-En-4-yn Carbonates Leading to 2,3,5-Trienoates
G. E. Akpınar, M. Kuş, M. Uçncu, E. Karakuş, L. Artok, Org. Lett., 2011, 13, 748-751.
Key Words
carboxylation, allenes, dienes
ID: J42-Y2014
