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An Efficient and Facile Synthesis of Vinyl Sulfones via Microwave-Assisted Copper Triflate Catalyzed Hydrosulfonylation of Alkynes

Ganesh M. Shelke, V. Kameswara Rao, Kasiviswanadharaju Pericherla, Anil Kumar*

*Department of Chemistry, Birla Institute of Technology and Science, Pilani 333031, Rajasthan, India, Email: anilkumarpilani.bits-pilani.ac.in

G. M. Shelke, V. K. Rao, K. Pericherla, A. Kumar, Synlett, 2014, 25, 2345-2349.

DOI: 10.1055/s-0034-1378546 (free Supporting Information)


Abstract

An efficient hydrosulfonylation of alkynes using sodium arene sulfinates is catalyzed by Cu(OTf)2 under microwave irradiation.Various vinyl sulfones were obtained in very good yields and with high regio- and stereoselectivity. Short reaction times, simple reaction conditions and low catalyst loading are the remarkable features of this protocol.

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Key Words

microwave synthesis, vinyl sulfones, copper triflate, alkynes, sodium arene sulfinates


ID: J60-Y2014