An Efficient and Facile Synthesis of Vinyl Sulfones via Microwave-Assisted Copper Triflate Catalyzed Hydrosulfonylation of Alkynes
Ganesh M. Shelke, V. Kameswara Rao, Kasiviswanadharaju Pericherla, Anil Kumar*
*Department of Chemistry, Birla Institute of Technology and
Science, Pilani 333031, Rajasthan, India, Email: anilkumar
pilani.bits-pilani.ac.in
G. M. Shelke, V. K. Rao, K. Pericherla, A. Kumar, Synlett, 2014, 25, 2345-2349.
DOI: 10.1055/s-0034-1378546
Abstract
An efficient hydrosulfonylation of alkynes using sodium arene sulfinates is catalyzed by Cu(OTf)2 under microwave irradiation.Various vinyl sulfones were obtained in very good yields and with high regio- and stereoselectivity. Short reaction times, simple reaction conditions and low catalyst loading are the remarkable features of this protocol.
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Key Words
microwave synthesis, vinyl sulfones, copper triflate, alkynes, sodium arene sulfinates
ID: J60-Y2014
