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Silyl Phosphorus and Nitrogen Donor Chelates for Homogeneous Ortho Borylation Catalysis

Behnaz Ghaffari, Sean M. Preshlock, Donald L. Plattner, Richard J. Staples, Peter E. Maligres, Shane W. Krska*, Robert E. Maleczka, Jr.*, and Milton R. Smith, III*

*Michigan State University, East Lansing, Michigan 48824-1322; Merck Research Laboratories, Rahway, New Jersey 07065, United States, Email:,,

B. Ghaffari, S. M. Preshlock, D. L. Plattner, R. J. Staples, P. E. Maligres, S. W. Krska, R. E. Maleczka, Jr., M. R. Smith, III, J. Am. Chem. Soc., 2014, 136, 14345-14348.

DOI: 10.1021/ja506229s (free Supporting Information)

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Ir complexes with bidentate silyl ligands that contain P- or N-donors are effective catalysts for ortho borylations of a broad range of substituted aromatics. The substrate scope is broad, and the modular ligand synthesis allows for flexible catalyst design.

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Key Words


ID: J48-Y2014