Copper-Catalyzed Aerobic Synthesis of 2-Arylpyridines from Acetophenones and 1,3-Diaminopropane
Long-Yi Xi, Ruo-Yi Zhang, Shuai Liang, Shan-Yong Chen* and Xiao-Qi Yu*
*Key Laboratory of Green Chemistry and Technology, Ministry
of Education, College of Chemistry, Sichuan University, Chengdu, Sichuan 610064,
P. R. China, Email: chensy
scu.edu.cn, xqyuscu.edu.cn
L.-Y. Xi, R.-Y. Zhang, S. Liang, S.-Y. Chen, X.-Q. Yu, Org. Lett., 2014, 16, 5269-5271.
DOI: 10.1021/ol5023596
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Abstract
A copper-catalyzed reaction of acetophenones and 1,3-diaminopropane provides direct access to 2-arylpyridines. A range of electronically diverse acetophenones undergo this transformation, affording 2-arylpyridines in good yields.
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Key Words
ID: J54-Y2014
