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Copper-Catalyzed, C-C Coupling-Based One-Pot Tandem Reactions for the Synthesis of Benzofurans Using o-Iodophenols, Acyl Chlorides, and Phosphorus Ylides

Yunyun Liu*, Hang Wang and Jie-Ping Wan*

*Ministry of Education and College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang 330022, P. R. China, Email: chemliuyunyunjxnu.edu.cn, wanjiepingjxnu.edu.cn

Y. Liu, H. Wang, J.-P. Wan, J. Org. Chem., 2014, 79, 10599-10604.

DOI: 10.1021/jo5017508 (free Supporting Information)


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Abstract

One-pot reactions of acyl chlorides, phosphorus ylides, and o-iodophenols in the presence of a copper catalyst enable a rapid synthesis of functionalized benzofurans.

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Key Words

benzofurans


ID: J42-Y2014