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Synthesis of Diarylmethanes through Palladium-Catalyzed Coupling of Benzylic Phosphates with Arylsilanes

Pengbo Zhang, Jian Xu, Yuzhen Gao, Xueqin Li, Guo Tang*, Yufen Zhao

*Department of Chemistry, College of Chemistry and Chemical Engineering, and the Key Laboratory for Chemical Biology of Fujian Province, Xiamen University, Xiamen, Fujian 361005, P. R. of China, Email:

P. Zhang, J. Xu, Y. Gao, X. Li, G. Tang, Y. Zhao, Synlett, 2014, 25, 2928-2932.

DOI: 10.1055/s-0034-1379366 (free Supporting Information)


An efficient Pd-catalyzed coupling of benzylic phosphates with arylsilanes provides straightforward access to diarylmethanes in very good yields. The reaction tolerates a wide range of functionalities such as halide, alkoxyl, and nitro groups.

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Key Words

palladium, diarylmethanes, arenes, benzylation, Hiyama cross-coupling

ID: J60-Y2014