Application of Bidentate Oxazoline-Carbene Ligands with Planar and Central Chirality in Asymmetric β-Boration of α,β-Unsaturated Esters
Zonghong Niu, Jianqiang Chen, Zhen Chen, Manyuan Ma, Chun Song* and Yudao Ma*
*Department of Chemistry, Shandong University, Shanda South
Road No. 27, Jinan 250100, P. R. China, Email: chunsong
sdu.edu.cn,
ydmasdu.edu.cn
Z. Niu, J. Chen, Z. Chen, M. Ma, C. Song, Y. Ma, J. Org. Chem., 2015, 80, 602-608.
DOI: 10.1021/jo5021135
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Abstract
Bidentate Oxazoline-substituted imidazolium salts based on [2.2]paracyclophane with planar and central chirality can be used as ligand in Cu(I)-catalyzed asymmetric β-boration of α,β-unsaturated esters, giving the desired products in high enantioselectivities and yields.
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Key Words
boration, hydroxylation, sodium perborate
ID: J42-Y2015
