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Copper Nanopowder Catalyzed Cross-Coupling of Diaryl Disulfides with Aryl Iodides in PEG-400

Xiang-mei Wu*, Guo-bing Yan

*Department of Chemistry, College of Ecology, Lishui University, Lishui, Zhejiang 323000, P. R. of China, Email:

X.-m. Wu, G.-b. Yan, Synlett, 2015, 26, 537-542.

DOI: 10.1055/s-0034-1379878


An eco-friendly coupling of diaryl disulfides and aryl iodides under ligand-free conditions with copper nanopowder as catalyst and PEG-400 as solvent enables the synthesis of varous unsymmetrical diaryl in very good yields. The process is odour-free and the copper nanopowder-PEG-400 catalytic system can be directly reused for four repetitive cycles.

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Key Words

diaryl sulfides, diaryl disulfides, aryl iodides, cross-coupling reaction, copper, green chemistry

ID: J60-Y2015