Dichlorination of α-Diazo-β-dicarbonyls Using (Dichloroiodo)benzene
Keith E. Coffey, Graham K. Murphy*
*Department of Chemistry, University of Waterloo, 200 University Ave W., Waterloo, ON, N2L 3G1, Canada, Email: graham.murphyuwaterloo.ca
K. E. Coffrey, G. K. Murphy, Synlett, 2015, 26, 1003-1007.
see article for more reactions
α-Diazo-β-dicarbonyl compounds were chlorinated using (dichloro)iodobenzene and an activating catalyst. Acyclic diazocarbonyls reacted faster than cyclics, and β-diketones were much faster to react than β-keto esters or β-diesters.
see article for more examples
J. Tao, R. Tran, G. K. Murphy, J. Am. Chem. Soc., 2013, 135, 16312-16315.