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Regioselective Synthesis of Multisubstituted Furans via Copper-Mediated Coupling between Ketones and β-Nitrostyrenes

Monoranjan Ghosh, Subhajit Mishra and Alakananda Hajra*

*Department of Chemistry, Visva-Bharati (A Central University), Santiniketan 731235, India, Email:

M. Ghosh, S. Mishra, A. Hajra, J. Org. Chem., 2015, 80, 5364-5368.

DOI: 10.1021/acs.joc.5b00704

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A copper-mediated intermolecular annulation of alkyl ketones and β-nitrostyrenes enables a regioselective synthesis of multisubstituted furan derivatives in good yields.

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Key Words

furans, TBHP, oxygen

ID: J42-Y2015