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Zn(salen)-Catalyzed Enantioselective Phenyl Transfer to Aldehydes and Ketones with Organozinc Reagent

Keisuke Shimizu, Hidenori Uetsu, Takashi Gotanda, Katsuji Ito*

*Department of Chemistry, Fukuoka University of Education, Akama, Munakata, Fukuoka, 811-4192, Japan, Email: itokatfukuoka-edu.ac.jp

K. Shimizu, H. Uetsu, T. Gotanda, K. Ito, Synlett, 2015, 26, 1238-1242.

DOI: 10.1055/s-0034-1380461 (free Supporting Information)


Abstract

A chiral zinc complex of salen is an efficient catalyst for the phenyl transfer from an organozinc reagent to aromatic aldehydes and acetophenones with high enantioselectivities.

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Key Words

Zn(salen) complex, asymmetric catalysis, phenyl transfer, aldehydes, ketones, diarylmethanol, 1,2-addition


ID: J60-Y2015