Organic Chemistry Portal

Abstracts

Search:

Ni-Catalyzed Regioselective Hydrocarboxylation of Alkynes with CO2 by Using Simple Alcohols as Proton Sources

Xueqiang Wang, Masaki Nakajima and Ruben Martin*

*Institute of Chemical Research of Catalonia (ICIQ), Av. Països Catalans 16, 43007 Tarragona, Spain, Email: rmartinromoiciq.es

X. Wang, M. Nakajima, R. Martin, J. Am. Chem. Soc., 2015, 137, 8924-8927.

DOI: 10.1021/jacs.5b05513


see article for more reactions

Abstract

A mild and user-friendly Ni-catalyzed regioselective hydrocarboxylation enables a regioselective conversion of a broad range of alkynes with CO2 (1 bar) while obviating the need for sensitive organometallic species and using simple alcohols as proton sources.

see article for more examples



Key Words

α,β-unsaturated compounds, manganese


ID: J48-Y2015