Metal-Free Direct Oxidation of Aldehydes to Esters Using TCCA
Silvia Gaspa, Andrea Porcheddu and Lidia De Luca*
*Dipartimento di Chimica e Farmacia, Università degli Studi
di Sassari, Via Vienna 2, 07100 Sassari, Italy, Email: ldeluca
uniss.it
S. Gaspa, A. Porcheddu, L. De Luca, Org. Lett., 2015, 17, 3666-3669.
DOI: 10.1021/acs.orglett.5b01579
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Abstract
In a mild and efficient oxidative esterification using TCCA as the oxidant, aromatic and aliphatic aldehydes are converted in situ into their corresponding acyl chlorides, which are then reacted with primary and secondary aliphatic, benzylic, allylic, and propargylic alcohols and phenols to give various esters in high yields.
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Key Words
oxidative esterification, TCCA
ID: J54-Y2015
