Divergent Synthesis of 2-Aminofurans via Palladium-Catalyzed Acetoxylative, Alkoxylative, and Hydroxylative Cycloisomerization of Homoallenyl Amides
Cungui Cheng, Shuiyou Liu and Gangguo Zhu*
*Department of Chemistry, Zhejiang Normal University, 688 Yingbin Road, Jinhua 321004, China, Email: gangguozjnu.cn
C. Cheng, S. Liu, G. Zhu, J. Org. Chem., 2015, 80, 7604-7612.
DOI: 10.1021/acs.joc.5b01182 (free Supporting Information)
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Hypervalent iodine compounds enable Pd-catalyzed acetoxylative, alkoxylative, and hydroxylative cycloisomerizations of homoallenyl amides to give three different types of polysubstituted 2-aminofurans in promising yields at room temperature.
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