Ascorbic Acid Promoted Oxidative Arylation of Vinyl Arenes to 2-Aryl Acetophenones without Irradiation at Room Temperature under Aerobic Conditions
Biju Majhi, Debasish Kundu and Brindaban C. Ranu*
*Department of Organic Chemistry, Indian Association for the
Cultivation of Science, Jadavpur, Kolkata 700032, India,
Email: ocbcr
iacs.res.in
B. Majhi, D. Kundu, B. C. Ranu, J. Org. Chem., 2015, 80, 7739-7745.
DOI: 10.1021/acs.joc.5b00825
Abstract
Aryl radicals generated in situ from arene diazonium fluoroborates promoted by ascorbic acid enable a convenient and general oxidative arylation of vinyl arenes in air at room temperature in the absence of any additive and visible light irradiation. Various 2-aryl acetophenones have been obtained in good yields.
see article for more examples
While ads financed 62% of the published abstracts in 2024, donations allowed us to publish additional 12%. 26% of the abstracts have been published voluntarly. If you kindly donate, we can publish more freely accessible information and help the chemical community even more:
If you don't like pawalls or a flood of more and more advertising, then you can send a clear signal here!
Key Words
Arylation, Oxidation, Oxygen, Ascorbic Acid
ID: J42-Y2015
