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Rh-Catalyzed Domino Addition-Enolate Arylation: Generation of 3-Substituted Oxindoles via a Rh(lll) Intermediate

Young Jin Jang, Hyung Yoon and Mark Lautens*

*Davenport Research Laboratories, Department of Chemistry, University of Toronto, Toronto M5S 3H6, Canada, Email: mlautenschem.utoronto.ca

Y. J. Jang, H. Yoon, M. Lautens, Org. Lett., 2015, 17, 3895-3897.

DOI: 10.1021/acs.orglett.5b01737 (free Supporting Information)


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Abstract

A Rh-catalyzed domino conjugate addition-arylation sequence enables the synthesis of 3-substituted oxindole derivatives in good yields via an intramolecular oxidative addition of a rhodium enolate.

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Key Words

oxindoles


ID: J54-Y2015