Rh-Catalyzed Domino Addition-Enolate Arylation: Generation of 3-Substituted Oxindoles via a Rh(lll) Intermediate
Young Jin Jang, Hyung Yoon and Mark Lautens*
*Davenport Research Laboratories, Department of Chemistry, University of Toronto, Toronto M5S 3H6, Canada, Email: mlautenschem.utoronto.ca
Y. J. Jang, H. Yoon, M. Lautens, Org. Lett., 2015, 17, 3895-3897.
DOI: 10.1021/acs.orglett.5b01737
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Abstract
A Rh-catalyzed domino conjugate addition-arylation sequence enables the synthesis of 3-substituted oxindole derivatives in good yields via an intramolecular oxidative addition of a rhodium enolate.
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Key Words
ID: J54-Y2015