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Chromatography-Free and Eco-Friendly Synthesis of Aryl Tosylates and Mesylates

Xiangyang Lei*, Anusha Jalla, Mhd A. Abou Shama, Jamie M. Stafford, Billy Cao

*Department of Chemistry and Biochemistry, Lamar University, Beaumont, TX 77710, USA, Email: xleilamar.edu

X. Lei, A. Jalla, M. A. A. Shama, J. M. Stafford, B. Cao, Synthesis, 2015, 47, 2578-2585.

DOI: 10.1055/s-0034-1378867


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Abstract

Two chromatography-free and eco-friendly protocols for tosylation and mesylation of phenols offer simplicity, short reaction time, mild conditions, and environmental friendliness. The reactions transform a broad range of substrates in excellent yields.

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Key Words

aryl tosylates, aryl mesylates, tosylation, mesylation, sulfonylation, green chemistry


ID: J66-Y2015