Organic Chemistry Portal



Copper-Catalyzed Thioetherification Reactions of Alkyl Halides, Triphenyltin Chloride, and Arylboronic Acids with Nitroarenes in the Presence of Sulfur Sources

Abed Rostami, Amin Rostami* and Arash Ghaderi*

*University of Kurdistan, Sanandaj 66177-15175; Hormozgan University, Bandar Abbas 71961, Iran, Email:,

A. Rostami, A. Rostami, A. Ghaderi, J. Org. Chem., 2015, 80, 8694-8704.

DOI: 10.1021/acs.joc.5b01248

see article for more reactions


In three odorless methods for the thioarylation and thioalkylation of different nitroarenes using alkyl halides (Br, Cl), triphenyltin chloride, and arylboronic acids as the coupling partners, Na2S2O35H2O, S8/KF, and S8/NaOH systems are found to be effective sources of sulfur in the presence of copper salts. The methods offer use of green solvents, inexpensive catalysts, and user-friendly starting materials.

see article for more examples

Key Words

aryl sulfides, alkyl sulfides, benzyl sulfides, green chemistry

ID: J42-Y2015