An Improved Synthesis of 2-Aryl- and 2-Alkenyl-1,3,4-oxadiazoles by Using Copper(II) Oxide Nanoparticles as a Catalyst
N. Salva Reddy, P. Raghavendar Reddy, Biswanath Das*
*Natural Products Chemistry Division, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, India, Email: biswanathdasyahoo.com
N. S. Reddy, P. R. Reddy, B. Das, Synthesis, 2015, 47, 2831-2838.
DOI: 10.1055/s-0034-1380923 (free Supporting Information)
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2-Aryl- and 2-alkenyl-1,3,4-oxadiazoles were efficiently synthesized in high yields by treatment of 1,3,4-oxadiazoles with aryl or alkenyl halides, respectively, in the presence of copper(II) oxide nanoparticles as reusable catalyst.
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1,3,4-oxadiazoles, copper, catalysis, nanoparticles, arylations, alkenylations