Copper-Catalyzed Oxidative Coupling-Annulation: One-Pot Synthesis of Indolizines from 2-Alkylazaarenes with Alkenes
Jing-ling Liu, Ying Liang*, Heng-shan Wang, Ying-ming Pan*
*Guilin University of Electronic Technolegy, Guilin, 541004;
Guangxi Normal University, Guilin, 541004, P. R. of China, Email: yingl
aliyun.com,
panym2013hotmail.com
J.-l. Liu, Y.-L. Liang, H.-s. Wang, Y.-m. Pan, Synlett, 2015, 26, 2024-2028.
Abstract
A copper-catalyzed highly selective oxidative coupling-annulation of 2-alkylazaarenes with terminal alkenes provides a simple, efficient, and atom-economic synthesis of indolizines in good yields.
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Key Words
indolizines, alkenes, 2-alkylazaarenes, oxidative coupling, oxygen, annulation
ID: J60-Y2015
