Copper-Catalyzed Cross-Coupling of Allylboronic Acids with α-Diazoketones
Arindam Das, Dong Wang, Marie-Charlotte Belhomme and Kálmán J. Szabó*
*Department of Organic Chemistry, Arrhenius Laboratory,
Stockholm University, SE-10691 Stockholm, Sweden, Email: kalman
organ.su.se
A. Das, D. Wang, M.-C. Belhomme, K. J. Szabo, Org. Lett., 2015, 17, 4754-4757.
DOI: 10.1021/acs.orglett.5b02285
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Abstract
A copper-catalyzed cross-coupling of substituted allylboronic acids with α-diazoketones is highly regioselective, providing the branched allylic product. The process involves creation of a new C(sp3)-C(sp3) bond by retaining the keto functional group of the α-diazoketone precursor.
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Key Words
ID: J54-Y2015
