Photoinduced, Copper-Catalyzed Carbon-Carbon Bond Formation with Alkyl Electrophiles: Cyanation of Unactivated Secondary Alkyl Chlorides at Room Temperature
Tanvi S. Ratani, Shoshana Bachman, Gregory C. Fu* and Jonas C. Peters*
*Division of Chemistry and Chemical Engineering, California
Institute of Technology, Pasadena, California 91125, United States, Email: gcfu
caltech.edu,
jpeterscaltech.edu
T. S. Ratani, S. Bachman, G. C. Fu, J. C. Peters, J. Am. Chem. Soc., 2015, 137, 13902-13907.
DOI: 10.1021/jacs.5b08452
see article for more reactions
Abstract
In the presence of inexpensive CuI and a readily available light source (UVC compact fluorescent light bulb), a wide array of secondary alkyl halides undergo cyanation in good yield.
see article for more examples
Key Words
ID: J48-Y2015
