A Single-Reagent-Driven Multistep One-Pot Preparation of Thiazolines and 1,3-Thiazines from Aldoximes, Nitriles, and Carboxylic Acids
Shubhankar Bhattacharyya, Uma Pathak*
*Synthetic Chemistry Division, Defence R & D Establishment, Jhansi Road, Gwalior 474002, India, Email: sc_drderediffmail.com
S. Battacharyya, U. Pathak, Synthesis, 2015, 47, 3553-3560.
DOI: 10.1055/s-0035-1560459 (free Supporting Information)
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N-(ω-Bromoalkyl)dichlorothiophosphoramidates enable a single-reagent-driven multistep preparation of a wide range of 2-substituted thiazolines and 1,3-thiazines from aldoximes, nitriles, or carboxylic acids.
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heterocycles, sulfur, tandem reaction, green chemistry, cyclization, thiazolines