Rapid and Efficient Microwave-Assisted Hydrophosphinylation of Unactivated Alkenes with H-Phosphinic Acids without Added Metal or Radical Initiator
Panagiota Troupa, Georgia Katsiouleri, Stamatia Vassiliou*
*Laboratory of Organic Chemistry, Department of Chemistry, University of Athens, Panepistimiopolis, Zografou, 15701 Athens, Greece, Email: svassiliouchem.uoa.gr
P. Troupa, G. Katsiouleri, S. Vassiliou, Synlett, 2015, 26, 2714-2719.
DOI: 10.1055/s-0035-1560209 (free Supporting Information)
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A microwave-assisted hydrophosphinylation of unactivated alkenes with phosphinic acid and its derivatives under metal- and initiator-free conditions is operationally simple and seems to proceed via a radical mechanism. Good isolated yields were obtained using a reasonable excess of the appropriate reagent.
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