Copper N-Heterocyclic Carbene: A Catalyst for Aerobic Oxidation or Reduction Reactions
Le-Wu Zhan, Lei Han, Ping Xing and Biao Jiang*
*School of Chemical Engineering, Nanjing University of
Science and Technology, 200 Xiaolingwei, Nanjing 210094, China, Email: jiangb
mail.sioc.ac.cn
L.-W. Zhan, L. Han, P. Xing, B. Jiang, Org. Lett., 2015, 17, 5990-5993.
DOI: 10.1021/acs.orglett.5b02756
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Abstract
Copper N-heterocyclic carbene complexes serve as catalysts for both aerobic oxidation of alcohols to aldehydes and reduction of imines to amines. A one-pot tandem synthetic strategy affords useful secondary amines from benzylic alcohols and anilines via an oxidation-reduction strategy.
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Key Words
aldehydes, reductive amination, aryl amines, oxygen, PMHS
ID: J54-Y2015
