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Mild and Efficient Silver(I) Triflate Catalyzed Synthesis of 2-Aryl-2,3-dihydroquinolin-4(1H)-ones, and Their Antioxidant Activities

Rameshwar Prasad Pandit, Kavita Sharma, Yong Rok Lee*

*School of Chemical Engineering, Yeungnam University, Gyeongsan 712-749, Republic of Korea, Email:

R. P. Pandit, K. Sharma, Y R. Lee, Synthesis, 2015, 47, 3881-3890.

DOI: 10.1055/s-0035-1560322 (free Supporting Information)


A mild and efficient one-pot procedure starting from o-aminoacetophenones and aromatic aldehydes in the presence of silver(I) triflate provides various 2-aryl-2,3-dihydroquinolin-4(1H)-ones. This method has several advantages, such as the use of easily available starting materials, the efficiency of the catalyst, a simple operation, and tolerance of a wide range of functionality in the aldehydes.

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Key Words

o-aminoacetophenones, aldehydes, silver(I) triflate, condensation, quinolinones, antioxidants, 2,3-dihydroquinolin-4-ones

ID: J66-Y2015