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Zinc Iodide Catalyzed Synthesis of 3-Aminoimidazo[1,2-a]pyridines from 2-Aminopyridines and α-Amino Carbonyl Compounds

Xu Han, Chaowei Ma, Zhaoyang Wu, Guosheng Huang*

*State Key Laboratory of Applied Organic Chemistry, Department of Chemistry, Lanzhou University, Lanzhou, Gansu, 730000, P. R. of China, Email:

X. Han, C. Ma, Z. Wu, G. Huang, Synthesis, 2016, 48, 351-356.

DOI: 10.1055/s-0035-1560375


A zinc iodide catalyzed reaction of 2-aminopyridines and α-amino carbonyl compounds in the presence of oxygen affords 3-aminoimidazo[1,2-a]pyridines in good yields.

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Key Words

3-aminoimidazo[1,2-a]pyridines, imidazo[1,2-a]pyridines, zinc iodide, heterocycles, 2-aminopyridines, α-amino carbonyls, oxygen

ID: J66-Y2016