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A Palladium-Catalyzed Three-Component Synthesis of Arylmethylsulfonamides

Tamara Beisel, Georg Manolikakes*

*Department of Organic Chemistry and Chemical Biology, Goethe-University Frankfurt, Max-von-Laue-Strasse 7, 60438 Frankfurt am Main, Germany, Email: g.manolikakeschemie.uni-frankfurt.de

T. Beisel, G. Manolikakes, Synthesis, 2016, 48, 379-386.

DOI: 10.1055/s-0035-1560910


Abstract

A palladium-catalyzed three-component synthesis of arylmethylsulfonamide derivatives from sulfonamides, paraformaldehyde, and arylboronic acids is operationally simple and provides a broad range of structurally interesting sulfonamidomethyl compounds.

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Sulfonamides as Amine Component in the Petasis-Borono Mannich Reaction: A Concise Synthesis of α-Aryl- and α-Alkenylglycine Derivatives

A. M. Diehl, O. Ouadoudi, E. Andreadou, G. Manolikakes, Synthesis, 2018, 50, 3936-3946.


Key Words

multicomponent reactions, palladium, sulfonamides (sulfonamidation, arylation), Petasis reaction, paraformaldehyde, arylboronic acids


ID: J66-Y2016