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Pd/C-Catalyzed Aminocarbonylation of Aryl Iodides via Oxidative C-N Bond Activation of Tertiary Amines to Tertiary Amides

Rajendra S. Mane and Bhalchandra M. Bhanage*

*Department of Chemistry, Institute of Chemical Technology, Mumbai 400019, India, Email: bm.bhanageictmumbai.edu.in

R. S. Mane, B. M. Bhanage, J. Org. Chem., 2016, 81, 1223-1228.

DOI: 10.1021/acs.joc.5b02385 (free Supporting Information)


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Abstract

Pd/C catalyzes an oxidative N-dealkylation/carbonylation of tertiary amines to tertiary amides by using molecular oxygen as a sole oxidant without ligands, additives, bases, and cocatalysts. Various tertiary amines as well as aryl iodides provide desired products in very good yield.

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Key Words

aminocarbonylation


ID: J42-Y2016