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Copper-Catalyzed Negishi Coupling of Diarylzinc Reagents with Aryl Iodides

Surendra Thapa, Adarsh S. Vangala, Ramesh Giri*

*Department of Chemistry & Chemical Biology, The University of New Mexico, Albuquerque, NM 87131, USA, Email:

S. Thapa, A. S. Vangala, R. Giri, Synthesis, 2016, 48, 504-511.

DOI: 10.1055/s-0035-1560397


An efficient copper(I) iodide catalyzed cross-coupling of diarylzinc reagents with aryl iodides proceeds under ligand-free conditions at low catalyst loading (5 mol%) and tolerates various functional groups.

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Key Words

copper, cross-coupling, diarylzinc, ligand-free, Negishi coupling, biaryls

ID: J66-Y2016