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Copper-Catalyzed Hydroamination of Terminal Allenes

Rémi Blieck, Janet Bahri, Marc Taillefer* and Florian Monnier*

*Ecole Nationale Supérieure de Chimie De Montpellier, AM2N, 8 rue de l'Ecole Normale, Montpellier 34296 Cedex 5, France, Email:,

R. Blieck, J. Bahri, M. Taillefer, F. Monnier, Org. Lett., 2016, 18, 1482-1485.

DOI: 10.1021/acs.orglett.6b00452

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A ligand-free copper-catalyzed hydroamination of allenes with cyclic secondary amines or anilines derivatives provides (E)-allylamines under smooth conditions with total regio- and stereoselectivity.

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Key Words

allylic amines, arylamines

ID: J54-Y2016