Organic Chemistry Portal



Copper-Catalyzed Amidation of Arylboronic Acids with Nitriles

He Huang, Zhong-Tao Jiang, Yang Wu, Cheng-Yan Gan, Jin-Mei Li, Shi-Kai Xiang*, Chun Feng, Bi-Qin Wang, Wei-Te Yang

*College of Chemistry and Materials Science, Sichuan Normal University, Chengdu, 610068, P. R. of China, Email:

H. Huang, Z.-T. Jiang, Y. Wu, C.-Y. Gan, J.-M. Li, S.-K. Xiang, C. Feng, B.-Q. Wang, W.-T. Yang, Synlett, 2016, 27, 951-955.

DOI: 10.1055/s-0035-1561291

see article for more reactions


A copper-catalyzed amidation of arylboronic acids with nitriles provides an efficient and complementary methodology for the synthesis of a broad range of N-arylamides.

see article for more examples

Key Words

amides, nitriles, amidation, hydrolysis, copper, catalysis, hypervalent iodine compounds

ID: J60-Y2016