Amination of Diazocarbonyl Compounds: N-H Insertion under Metal-Free Conditions
Xuesong Luo, Gui Chen, Lin He* and Xueliang Huang*
*Shihezi University, Xinjiang Uygur Autonomous Region, 832000; Chinese Academy of Sciences, Fuzhou, Fujian 350002, China, Email: helinshzu.edu.cn, huangxlfjirsm.ac.cn
X. Luo, G. Chen, L. He, X. Huang, J. Org. Chem., 2016, 81, 2943-2949.
DOI: 10.1021/acs.joc.6b00233 (free Supporting Information)
see article for more reactions
Dibenzenesulfonimide is a nitrogen source of choice in terms of the yields and the reaction time in a transition-metal-free intermolecular N-H insertion of α-diazocarbonyl compounds. Primary mechanistic experiments suggest that a pathway involves a sequence of protonation and nucleophilic substitution.
see article for more examples