Organic Chemistry Portal

Abstracts

Search:

A Chiral Electrophilic Selenium Catalyst for Highly Enantioselective Oxidative Cyclization

Yu Kawamata, Takuya Hashimoto and Keiji Maruoka*

*Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502, Japan, Email: maruokakuchem.kyoto-u.ac.jp

Y. Kawamata, T. Hashimoto, K. Maruoka, J. Am. Chem. Soc., 2016, 138, 5206-5209.

DOI: 10.1021/jacs.6b01462 (free Supporting Information)


Abstract

A chiral electrophilic selenium catalyst based on a rigid indanol scaffold, which can be easily synthesized from a commercially available indanone, efficiently converts β,γ-unsaturated carboxylic acids into various enantioenriched γ-butenolides under mild conditions.

see article for more examples



Key Words

butenolides


ID: J48-Y2016