Phenyliodonium Diacetate Mediated Oxidative Functionalization of Styrenes with Molecular Oxygen: Synthesis of α-Oxygenated Ketones
Supravat Samanta, Ramachandra Reddy Donthiri, Chitrakar Ravi and Subbarayappa Adimurthy*
*Academy of Scientific & Innovative Research, CSIR-Central
Salt & Marine Chemicals Research Institute, G.B. Marg, Bhavnagar 364 002.
Gujarat, India, Email: adimurthy
csmcri.org
S. Samanta, R. R. Donthiri, C. Ravi, S. Adimurthy, J. Org. Chem., 2016, 81, 3457-3463.
DOI: 10.1021/acs.joc.6b00266
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Abstract
Phenyliodonium diacetate mediates a synthesis of α-oxygenated ketones from styrenes in the presence of molecular oxygen and N-hydroxyphthalimide or N-hydroxybenzotriazole under metal-free conditions. The present method is applicable for wide range of styrenes with various functional groups.
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Key Words
α-hydroxy ketones, α-hydroxylation, PIDA, oxygen
ID: J42-Y2016
