Organic Chemistry Portal

Abstracts

Search:

Gold-Catalyzed Anti-Markovnikov Selective Hydrothiolation of Unactivated Alkenes

Taichi Tamai, Keiko Fujiwara, Shinya Higashimae, Akihiro Nomoto and Akiya Ogawa*

*Department of Applied Chemistry, Graduate School of Engineering, Osaka Prefecture University, 1-1 Gakuen-cho, Nakaku, Sakai, Osaka 599-8531, Japan, Email: ogawachem.osakafu-u.ac.jp

T. Tamai, K. Fujiwara, S. Higashimae, A. Nomoto, A. Ogawa, Org. Lett., 2016, 18, 2114-2117.

DOI: 10.1021/acs.orglett.6b00746 (free Supporting Information)



see article for more reactions

Abstract

A gold-catalyzed hydrothiolation of unactivated alkenes proceeds effectively to give anti-Markovnikov-selective adducts in good yields and in a regioselective manner.

see article for more examples

proposed mechanism



Key Words

sulfides, aryl sulfides


ID: J54-Y2016