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Ni-Catalyzed Carboxylation of Unactivated Alkyl Chlorides with CO2

Marino Börjesson, Toni Moragas and Ruben Martin*

*Institute of Chemical Research of Catalonia (ICIQ), The Barcelona Institute of Science and Technology, Av. Països Catalans 16, 43007 Tarragona, Spain, Email:

M. Börjesson, T. Moragas, R. Martin, J. Am. Chem. Soc., 2016, 138, 7504-7507.

DOI: 10.1021/jacs.6b04088

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A catalytic carboxylation of unactivated primary, secondary, and tertiary alkyl chlorides with CO2 at atmospheric pressure features exquisite chemoselectivity, mild conditions and ease of execution.

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Y. Liu, J. Cornella, R. Martin, J. Am. Chem. Soc., 2014, 136, 11212-11215.

Ni-Catalyzed Direct Carboxylation of Benzyl Halides with CO2

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Key Words

carboxylation, manganese

ID: J48-Y2016