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Reaction between 4-Nitro-1,3-diarylbutan-1-ones and Ammonium Acetate in the Presence of Morpholine and Sulfur: An Efficient Synthesis of 2,4-Diarylpyrroles

Mehdi Adib*, Neda Ayashi, Fatemeh Heidari, Peiman Mirzaei

*School of Chemistry, College of Science, University of Tehran, P. O. Box 14155-6455, Tehran, Iran, Email:

M. Adib, N. Ayashi, F. Heidari, P. Mirzaei, Synlett, 2016, 27, 1738-1742.

DOI: 10.1055/s-0035-1561852

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The reaction of 4-nitro-1,3-diarylbutan-1-ones and ammonium acetate in the presence of morpholine and sulfur provides the corresponding 2,4-diarylpyrroles in excellent yields.

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Key Words

pyrroles, 2,4-diarylpyrroles, 4-nitro-1,3-diarylbutan-1-ones, morpholine, sulfur, heterocycles, cyclization

ID: J60-Y2016