Reaction between 4-Nitro-1,3-diarylbutan-1-ones and Ammonium Acetate in the Presence of Morpholine and Sulfur: An Efficient Synthesis of 2,4-Diarylpyrroles
Mehdi Adib*, Neda Ayashi, Fatemeh Heidari, Peiman Mirzaei
*School of Chemistry, College of Science, University of
Tehran, P. O. Box 14155-6455, Tehran, Iran, Email: madibkhayam.ut.ac.ir
M. Adib, N. Ayashi, F. Heidari, P. Mirzaei, Synlett, 2016, 27, 1738-1742.
see article for more reactions
Abstract
The reaction of 4-nitro-1,3-diarylbutan-1-ones and ammonium acetate in the presence of morpholine and sulfur provides the corresponding 2,4-diarylpyrroles in excellent yields.
see article for more examples
Key Words
pyrroles, 2,4-diarylpyrroles, 4-nitro-1,3-diarylbutan-1-ones, morpholine, sulfur, heterocycles, cyclization
ID: J60-Y2016