Synthesis of Sulfonyl Azides via Lewis Base Activation of Sulfonyl Fluorides and Trimethylsilyl Azide
Andrew S. Barrow, John E. Moses*
*School of Chemistry, University of Nottingham, University Park, Nottingham NG7 2RD, UK, Email: John.mosesnottingham.ac.uk
A. S. Barrow, J. E. Moses, Synlett, 2016, 27, 1840-1843.
DOI: 10.1055/s-0035-1561626 (free Supporting Information)
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Lewis base activation enables an opperationally simple protocol for the efficient conversion of sulfonyl fluorides into sulfonyl azides. The in situ generated sulfonyl azides are efficient diazo-transfer agents, affording primary azides and diazo compounds in excellent yields.
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sulfonyl azides, Lewis base, diazo-transfer, sulfonyl fluoride, SuFEx