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Co(II) PCP Pincer Complexes as Catalysts for the Alkylation of Aromatic Amines with Primary Alcohols

Matthias Mastalir, Gerald Tomsu, Ernst Pittenauer, GŁnter Allmaier and Karl Kirchner*

*Institute of Applied Synthetic Chemistry and Institute of Chemical Technologies and Analytics, Vienna University of Technology, Getreidemarkt 9/163-AC, A-1060 Wien, Austria, Email:

M. Mastalir, G. Tomsu, E. Pittenauer, G. Allmaier, K. Kirchner, Org. Lett., 2016, 18, 3462-3465.

DOI: 10.1021/acs.orglett.6b01647

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Well-defined Co(II) complexes stabilized by a PCP ligand catalyze efficient alkylations of aromatic amines by primary alcohols into mono-N-alkylated amines in very good yields. The inexpensive, earth-abundant nonprecious metal catalysts make this acceptorless alcohol dehydrogenation concept environmentally benign.

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Key Words

arylamines, benzylamines, alkylation, green chemistry

ID: J54-Y2016