Iron-Catalyzed Acylation of Polyfunctionalized Aryl- and Benzylzinc Halides with Acid Chlorides

Andreas D. Benischke, Marcel Leroux, Irina Knoll and Paul Knochel*

*Department of Chemistry, Ludwig-Maximilians-Universität, Butenandtstrasse 5-13, 81377 Munich, Germany, Email: paul.knochelcup.uni-muenchen.de

A. D. Benischke, M. Leroux, I. Knoll, P. Knochel, Org. Lett., 2016, 18, 3626-3629.

DOI: 10.1021/acs.orglett.6b01677 (free Supporting Information)

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Abstract

FeCl₂ catalyzes a smooth and convenient acylation of functionalized arylzinc halides and benzylic zinc chlorides with various acid chlorides to provide polyfunctionalized diaryl and aryl benzyl ketones.

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Key Words

aryl ketones, acylation

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ID: J54-Y2016