Visible-Light Photoredox Catalyzed Three-Component Cyclization of 2H-Azirines, Alkynyl Bromides, and Molecular Oxygen to Oxazole Skeleton
Lili Chen, Hongji Li*, Pinhua Li and Lei Wang*
*Department of Chemistry, Huaibei Normal University, Huaibei,
Anhui 235000, P.R. China, Email: hongjili1982
163.com,
leiwang88hotmail.com
L . Chen, H. Li, P. Li, L. Wang, Org. Lett., 2016, 18, 3646-3649.
DOI: 10.1021/acs.orglett.6b01696
Abstract
A three-component cyclization of 2H-azirines, alkynyl bromides, and molecular oxygen under visible-light photoredox catalysis at room temperature provides a wide range of substituted oxazoles in good yields.
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Key Words
oxazoles, multicomponent reactions, oxygen
ID: J54-Y2016
