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An Indefinitely Air-Stable σ-NiII Precatalyst for Quantitative Cross-Coupling of Unreactive Aryl Halides and Mesylates with Aryl Neopentylglycolboronates

Jagadeesh Malineni, Ryan L. Jezorek, Na Zhang, Virgil Percec*

*Roy & Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104-6323, USA, Email:

J. Malineni, R. L. Jezorek, N. Zhang, V. Percec, Synthesis, 2016, 48, 2795-2807.

DOI: 10.1055/s-0035-1562342

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A universal, bench-stable and easily prepared NiIICl(1-naphthyl)(PCy3)2/PCy3 σ-complex enables efficient and quantitative cross-coupling of aryl chlorides, bromides, iodides, mesylates, and fluorides with aryl neopentylglycolboronates.

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Key Words

nickel, Suzuki coupling, quantitative, aryl chlorides, aryl bromides, aryl fluorides, aryl mesylates, biaryls

ID: J66-Y2016