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Copper-Catalyzed N-Arylation of 2-Pyridones Employing Diaryliodonium Salts at Room Temperature

Seo-Hee Jung, Dan-Bi Sung, Cho-Hee Park and Won-Suk Kim*

*Department of Chemistry and Nano Science, Ewha Womans University, Seoul 120-750, South Korea, Email:

S.-H. Jung, D.-B. Sung, C.-H. Park, W.-S. Kim, J. Org. Chem., 2016, 81, 7717-7724.

DOI: 10.1021/acs.joc.6b01415

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A mild Cu-catalyzed approach for the N-arylation of 2-pyridones with diaryliodonium salts proceeds readily at room temperature to provide N-arylpyridine-2-ones in very good yields.

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Key Words

N-Arylation, 2-Pyridones

ID: J42-Y2016