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Rhodium-Catalyzed Annulation of Primary Benzylamine with α-Diazo Ketone toward Isoquinoline

Haoke Chu, Peiran Xue, Jin-Tao Yu and Jiang Cheng*

*School of Petrochemical Engineering, Changzhou University, Changzhou 213164, P. R. China, Email: jiangchengcczu.edu.cn

H. Chu, P. Xue, J.-T. Yu, J. Cheng, J. Org. Chem., 2016, 81, 8009-8013.

DOI: 10.1021/acs.joc.6b01378 (free Supporting Information)


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Abstract

A regioselective rhodium-catalyzed annulation of commercially available primary benzylamines with α-diazo compounds provides isoquinolines in good yields.

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Key Words

isoquinolines


ID: J42-Y2016