Synthesis of Enantioenriched Pyrrolidines via Gold-Catalyzed Tandem Cycloisomerization/Hydrogenation of Chiral Homopropargyl Sulfonamides
Yong-Fei Yu, Chao Shu, Tong-De Tan, Long Li, Shahid Rafique and Long-Wu Ye*
*College of Chemistry and Chemical Engineering, Xiamen
University, Xiamen 361005, China, Email: longwuye
xmu.edu.cn
Y.-F. Yu, C. Shu, T.-D. Tan, L. Li, S. Rafique, L.-W. Ye, Org. Lett., 2016, 18, 5178-5181.
DOI: 10.1021/acs.orglett.6b02736
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Abstract
A novel gold-catalyzed tandem cycloisomerization/hydrogenation of chiral homopropargyl sulfonamides provides various enantioenriched pyrrolidines in excellent yields and excellent enantioselectivities.
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Key Words
ID: J54-Y2016
