Borane-Catalyzed Transfer Hydrogenations of Pyridines with Ammonia Borane
Qiwen Zhou, Lanqiong Zhang, Wei Meng, Xiangqing Feng, Jing Yang* and Haifeng Du*
*College of Life Science and Technology, Beijing University
of Chemical Technology, Beijing 100029; Institute of Chemistry, Chinese Academy
of Sciences, Beijing 100190, China, Email: yangj
mail.buct.edu.cn,
haifengduiccas.ac.cn
Q. Zhou, L. Zhang, W. Meng, X. Feng, J. Yang, H. Du, Org. Lett., 2016, 18, 5189-5191.
DOI: 10.1021/acs.orglett.6b02610
see article for more reactions
Abstract
A borane catalyzed metal-free transfer hydrogenation of pyridines furnishes various piperidines in good yields with good cis-selectivities in the presence of ammonia borane as a hydrogen source. The ease in handling without requiring high pressure H2 makes this transfer hydrogenation practical and useful.
see article for more examples
Key Words
ID: J54-Y2016
