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Self-Assembled Nanoliposomes of Phosphatidylcholine: Bridging the Gap between Organic and Aqueous Media for a Green Synthesis of Hydroquinazolinones

Fatemeh Tamaddon*, MohammadTaghi KazemiVarnamkhasti

*Department of Chemistry, Yazd University, Yazd 89195-741, Iran, Email:

F. Tamaddon, M. KazemiVernamkhasti, Synlett, 2016, 27, 2510-2514.

DOI: 10.1055/s-0035-1562604

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Self-assembly of phosphatidylcholine in water creates liposomal nanoreactors for environmentally friendly synthesis of hydroquinazolinones by two- or three-component reactions, without the use of an extra catalyst or solvent. The reaction medium can be recycled.

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Key Words

liposomes, self-assembly, nanoreactors, phosphatidylcholine, hydroquinazolinones, 2,3-dihydroquinazolinones, green chemistry

ID: J60-Y2016