Palladium-Catalyzed Highly Regio- and Enantioselective Hydroesterification of Aryl Olefins with Phenyl Formate
Jingfu Li, Wenju Chang, Wenlong Ren, Jie Dai and Yian Shi*
*Department of Chemistry, Colorado State University, Fort
Collins, Colorado 80523, United States, Email: Yian.Shi
colostate.edu
J. Li, W. Chang, W. Ren, J. Dai, Y. Shi, Org. Lett., 2016, 18, 5456-5459.
DOI: 10.1021/acs.orglett.6b02467
see article for more reactions
Abstract
An effective Pd-catalyzed regio- and enantioselective hydroesterification of aryl olefins with phenyl formate provides phenyl 2-arylpropanoates in good yields with high b/l ratios and ee's without using toxic CO gas.
see article for more examples
ligand
W. Liu, W. Ren, J. Li, Y. Shi, W. Chang, Y. Shi, Org. Lett., 2017, 19, 1748-1751.
An Effective Pd-Catalyzed Regioselective Hydroformylation of Olefins with Formic Acid
W. Ren, W. Chang, J. Dai, Y. Shi, J. Li, Y. Shi, J. Am. Chem. Soc., 2016, 138, 14864-14867.
Pd-Catalyzed Regiodivergent Hydroesterification of Aryl Olefins with Phenyl Formate
W. Ren, W. Chang, Y. Wang, J. Li, Y. Shi, Org. Lett., 2015, 17, 3544-3547.
Key Words
ID: J54-Y2016
