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Palladium-Catalyzed Highly Regio- and Enantioselective Hydroesterification of Aryl Olefins with Phenyl Formate

Jingfu Li, Wenju Chang, Wenlong Ren, Jie Dai and Yian Shi*

*Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, United States, Email: Yian.Shicolostate.edu

J. Li, W. Chang, W. Ren, J. Dai, Y. Shi, Org. Lett., 2016, 18, 5456-5459.

DOI: 10.1021/acs.orglett.6b02467 (free Supporting Information)


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Abstract

An effective Pd-catalyzed regio- and enantioselective hydroesterification of aryl olefins with phenyl formate provides phenyl 2-arylpropanoates in good yields with high b/l ratios and ee's without using toxic CO gas.

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ligand



A Ligand-Directed Catalytic Regioselective Hydrocarboxylation of Aryl Olefins with Pd and Formic Acid

W. Liu, W. Ren, J. Li, Y. Shi, W. Chang, Y. Shi, Org. Lett., 2017, 19, 1748-1751.

An Effective Pd-Catalyzed Regioselective Hydroformylation of Olefins with Formic Acid

W. Ren, W. Chang, J. Dai, Y. Shi, J. Li, Y. Shi, J. Am. Chem. Soc., 2016, 138, 14864-14867.

Pd-Catalyzed Regiodivergent Hydroesterification of Aryl Olefins with Phenyl Formate

W. Ren, W. Chang, Y. Wang, J. Li, Y. Shi, Org. Lett., 2015, 17, 3544-3547.


Key Words

esters


ID: J54-Y2016